Low Rates of Coronary Artery Disease in People with HIV — Uganda

Among older PWH on antiretroviral therapy in Uganda, incidence of coronary artery disease was dramatically lower than has been reported in Global North Countries.

Morbidity and mortality from coronary artery disease (CAD) is a major concern for people with HIV (PWH) in the U.S. and Europe, with prevention a focus after publication of the REPRIEVE trial. As data on CAD among PWH in middle- and low-income countries have been limited, investigators from Uganda performed cardiovascular disease (CVD) profiling and computed tomography scanning of coronary arteries to detect CAD (defined as presence of calcified or noncalcified plaque) in a circumscribed population of PWH (older than 40 years; on ART ≥3 years) and a matched control population without HIV (PWoH).

The enrolled groups consisted of 287 PWH (95% of whom had HIV levels <40 copies/mL) and 299 PWoH. Characteristics of PWH and PWoH were: Mean age, 58…

Reviewing Author

Keith Henry, MD

Disclosures

Consultant/Advisory BoardViiV Advisory Board

Editorial BoardsJAIDS: Journal of Acquired Immune Deficiency Syndromes

Keith Henry, MD

Disclosures

Consultant/Advisory BoardViiV Advisory Board

Editorial BoardsJAIDS: Journal of Acquired Immune Deficiency Syndromes

Low Rates of Coronary Artery Disease in People with HIV — Uganda

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Reviewing Author