Updated Long-Term Outlook After Transient Ischemic Attack or Minor Stroke

The 5-year risk for stroke after a TIA or minor stroke is 12.5%, according to a meta-analysis of contemporary studies — better than before, but still significant.

Data from older studies suggest that 1 in 3 patients will experience a stroke within 5 years after a transient ischemic attack (TIA). Now, researchers have conducted a meta-analysis of more-contemporary studies to determine 5- and 10-year outcomes after a TIA or minor stroke.

The analysis included 38 studies, 71% of which enrolled patients in or after 2007, with a total of 171,068 patients (median age, 69 years; 57% men). The rate of subsequent stroke per 100 person-years was 5.94 events in the first year, 1.80 annually in years 2–5, and 1.72 annually in years 6–10. The overall 5-year rate of stroke was 12.5%, and the 10-year rate was 19.8%. Ten percent of the subsequent strokes were fatal events. Stroke rates were lower after a TIA than in …

Reviewing Author

Seemant Chaturvedi, MD

Disclosures

Consultant/Advisory BoardBayer Pharmaceuticals; Novartis

Grant/Research SupportNational Institute of Neurological Disorders and Stroke

Editorial BoardsNeurology; Stroke

Seemant Chaturvedi, MD

Disclosures

Consultant/Advisory BoardBayer Pharmaceuticals; Novartis

Grant/Research SupportNational Institute of Neurological Disorders and Stroke

Editorial BoardsNeurology; Stroke

Updated Long-Term Outlook After Transient Ischemic Attack or Minor Stroke

Topics

Reviewing Author