Primary Aldosteronism: Updated Screening and Management Recommendations from the Endocrine Society

Background

Identifying and treating primary aldosteronism — an underrecognized and undertreated secondary cause of hypertension — is critical to mitigate excess risk associated with this condition. This Endocrine Society guideline is an update to its 2016 guideline on managing primary aldosteronism (J Clin Endocrinol Metab 2016; 101:1889).

Key Points

• Screening for primary aldosteronism with aldosterone and renin levels is suggested for all patients with hypertension.

• Helpful strategies to address factors that contribute to false negative or false positive results, such as hypokalemia and interfering medications, are provided.

• Patients can be categorized as having low, intermediate, or high probability of…