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An overview of the 2025 Epinephrine and Emergency Medical Services Activation Recommendations during Acute Allergic Reactions in Community Settings: International Consensus Report
Most patients and clinicians recognize self-administered epinephrine as the gold standard, first-line treatment for anaphylaxis; however, uncertainty remains about which symptoms warrant its use and when medical attention is necessary (see ). To address this gap, an international panel developed scenario-based recommendations for managing acute allergic reactions at home or in other community settings.
Administer epinephrine if the patient has:
Any cardiovascular or neurological symptoms, such as altered responsiveness, dizziness,…