A New Wearable Device for Essential Tremor

For some patients with essential tremor, medications yield unsatisfactory results, and neurostimulation (e.g., deep brain stimulation) is considered. In July 2025, the U.S. FDA approved a new wearable device, marketed as Felix NeuroAI Wristband, that uses transcutaneous peripheral nerve stimulation (TPNS).

In the study that led to approval, researchers randomized 125 patients (mean age, 65; average tremor duration, 11 years) to either TPNS or sham device. The primary outcome was a composite measure of self-reported difficulty with 10 activities of daily living (e.g., drinking from a glass, dressing, writing) and 2 investigator-assessed drawing tasks (spirals, handwriting); the maximum score was 52.