Registry data show that the rate of late PCI on completely occluded arteries did not decline after the OAT findings prompted guideline recommendations against it.
The 2006 Occluded Artery Trial (OAT) demonstrated no benefit of percutaneous coronary intervention (PCI) to treat completely occluded culprit arteries >24 hours after acute myocardial infarction (MI; JW Cardiol Nov 14 2006).
Consequently, the 2007 American College of Cardiology/American Heart Association guidelines for ST-segment-elevation MI (STEMI), non-STEMI, and PCI include class III recommendations against such treatment. To what extent have the OAT results and the guideline recommendations been incorporated into practice?
Using National Cardiovascular Data Registry (CathPCI) data, investigators identified 28,780 patients with at least one total coronary occlusion and no reported OAT exclusion characteristics who underwent angiography >2…
Reviewing Author
DisclosuresConsultant/Advisory BoardBristol Myers Squibb; CPC Clinical Research
Grant/Research SupportNational Heart, Lung, and Blood Institute
Editorial BoardsUpToDate; American College of Cardiology Self-Assessment Program (SAP)
Leadership Positions in Professional SocietiesAmerican College of Cardiology (Chair, Innovations Committee)
DisclosuresConsultant/Advisory BoardBristol Myers Squibb; CPC Clinical Research
Grant/Research SupportNational Heart, Lung, and Blood Institute
Editorial BoardsUpToDate; American College of Cardiology Self-Assessment Program (SAP)
Leadership Positions in Professional SocietiesAmerican College of Cardiology (Chair, Innovations Committee)