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A 57-year-old woman first presented with a severe headache and tonic-clonic seizures, with CT imaging showing hyperdensities of the left parietal lobe that were suspicious for subarachnoid hemorrhage. Follow-up imaging was consistent with an arteriovenous fistula, which was embolized. However, in the next 6 months, she experienced worsening seizures and cranial neuropathies. Brain MRI revealed intrinsic T1 hyperintensities (see ), and cerebrospinal fluid studies were unremarkable. A meningeal biopsy confirmed a primary melanocytic tumor.
Comment
The differential diagnosis in this case was significantly narrowed by the presence of intrinsic (e.g., seen without gadolinium) hyperintensities on brain MRI. These imaging findings must invol…