Pimecrolimus for Steroid Rosacea

This calcineuron inhibitor produced good results during the study period, but long-term success is yet to be proved.

Some patients with rosacea, perioral dermatitis, or other conditions develop a rosacea-like eruption after treatment with topical corticosteroids, particularly fluorinated ones. Called steroid-induced rosacea or steroid rosacea, it appears as an eruption of papules and pustules on ruddy skin near the mouth. The eruption responds to resumption of topical steroids but usually flares again when treatment is stopped.

Lee and colleagues studied the effectiveness of pimecrolimus, a nonsteroidal anti-inflammatory agent, for steroid-induced rosacea in 18 subjects who had pruritic facial papules, pustules, erythema, and telangiectases after at least 2 weeks of treatment with topical corticosteroids. Patients with acne, rosacea, and other, possibly co…

Reviewing Author

Mark V. Dahl, MD

Disclosures

Consultant / Advisory board Ulthera, Inc.; AuBio LifeSciences, LLC; Paris Therapeutics

Equity Elorac, Inc.; Makucell, Inc.; Paris Therapeutics

Editorial boards UpToDate

Leadership positions in professional societiesNational Rosacea Society (Chairman, Medical Board)

Mark V. Dahl, MD

Disclosures

Consultant / Advisory board Ulthera, Inc.; AuBio LifeSciences, LLC; Paris Therapeutics

Equity Elorac, Inc.; Makucell, Inc.; Paris Therapeutics

Editorial boards UpToDate

Leadership positions in professional societiesNational Rosacea Society (Chairman, Medical Board)