Predictors of Rebleeding After Endoscopic Therapy for Peptic Ulcers

Risk factors were hemodynamic instability, a low hemoglobin value, active bleeding, large ulcer size, and an ulcer in the posterior duodenum or high on the lesser gastric curve.

Several scoring systems have been developed to predict rebleeding and mortality in patients with nonvariceal upper gastrointestinal bleeding (UGIB), but these scores were not designed to predict rebleeding after endoscopic therapy. Also, in a recent comprehensive review of endoscopic therapies for UGIB (JW Gastroenterol May 1 2009), risk factors for rebleeding were not covered.

To shed light on the issue, investigators performed a meta-analysis of studies that addressed postendoscopic therapy. Of 2193 relevant citations, 14 studies (12 full articles and 2 abstracts) involving 3609 patients met the prespecified inclusion criteria. Pooled results were calculated for factors identified by multivariate analysis in two or more studies.

Pre-endosco…

Reviewing Author

David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)

Disclosures

Nothing to disclose

David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)

Disclosures

Nothing to disclose

Predictors of Rebleeding After Endoscopic Therapy for Peptic Ulcers

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Reviewing Author