The radiograph shows a striking example of the reversed halo sign: a ground-glass opacity surrounded by a ring of denser consolidation. The angelic-appearing pattern belies its more-sinister nature as an indicator of several maladies, including cryptogenic organizing and bacterial pneumonia, autoimmune conditions, and malignancies. In immunocompromised patients, clinicians should consider it a warning sign for invasive fungal infections, specifically pulmonary mucormycosis. Other common imaging findings of pulmonary mucormycosis include consolidations, pleural effusions, halo signs, and cavitary lesions.
Comment
The radiograph shows a striking example of the reversed halo sign: a ground-glass opacity surrounded by a ring of denser consolidation. The angelic-appearing pattern belies its more-sinister nature as an indicator of several maladies, including cryptogenic organizing and bacterial pneumonia, autoimmune conditions, and malignancies. In immunocompromised patients, clinicians should consider it a warning sign for invasive fungal infections, specifically pulmonary mucormycosis. Other common imaging findings of pulmonary mucormycosis include consolidations, pleural effusions, halo signs, and cavitary lesions.