Sildenafil Works for Women with Sexual Arousal Problems

Sildenafil is a standard treatment for male erectile dysfunction, but its application in female sexual dysfunction remains uncertain. These Italian authors conducted a randomized, double-blind, crossover study to explore the use of sildenafil in 51 women (aged 22-38) with documented ovarian function who reported adequate sexual desire but decreased arousal.

Subjects were recruited from a sexual dysfunction clinic; each had a lack of vaginal lubrication and a lack of clitoral and vaginal sensation or slow sexual response. The women received 4-week regimens of 25-mg sildenafil, 50-mg sildenafil, and placebo in random order, with a 1-week washout between treatments; each tablet was to be taken 1 hour before intercourse, not more than once daily…