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HIV-positive patients are at increased risk for sinus infection. Two retrospective studies used data from large cohorts of HIV-infected patients to examine the characteristics of sinus infection.
In both cohorts, sinusitis was severe and more prevalent than commonly recognized. The most frequent symptoms included nasal congestion, fever, and postnasal drainage with or without headache. However, many patients were asymptomatic. Patients with CD4 cell counts below 200/cubic mm were more prone to sinus disease and had the most extensive disease, which often did not respond completely to antibiotic therapy.
These two studies clearly show that sinusitis in HIV- infected patients is common, that it may be recurrent, and that it is frequently not de…