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Adherence to drug regimens prescribed for young children is linked closely to the palatability of the drug. These U.S. investigators conducted a blinded taste test among 86 physicians; each physician tasted amoxicillin (the standard used for comparison) and 11 other antibiotic suspensions. Each suspension was judged on a scale of 0 (poorest acceptability) to 5 (highest acceptability) for appearance, smell, texture, taste, and aftertaste; the scores were combined into an adjusted overall rating for palatability.
Amoxicillin was assigned a mean score of 3. The other adjusted palatability scores were as follows: loracarbef (Lorabid), 3.25; cefdinir (Omnicef), 3.00; cefixime (Suprax), 2.77; azithromycin (Zithromax), 2.50; ciprofloxacin (Cipro), …