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Hemangioma is the most common tumor to affect infants, and ulceration is one of the most frequent complications. Despite the prevalence of this problem, its epidemiology is not well documented, its pathogenesis remains unexplored, and a uniform approach to therapy has not been defined. This paucity of clinical investigation inspired these authors to conduct a retrospective analysis of 60 patients with ulcerated hemangiomas seen over a 10-year period by a pediatric dermatologist at the University of California, San Francisco.
Ulceration was present upon initial evaluation in 90 percent of cases and developed thereafter in the rest. Most lesions were plaque-type, larger than 6 cm2, and located on the head and neck. One-third involved the perin…