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Neuromyotonia is a motor-nerve hyperactivity syndrome characterized by muscle contraction at rest and delayed muscle relaxation, sometimes accompanied by the continuous muscle rippling known as myokymia. Most patients have generalized muscle symptoms that often respond to sodium-channel-blocking drugs like carbamazepine. Nonhereditary cases are probably autoimmune in nature, associated with antibodies to voltage-gated potassium channels.
The authors of this brief report describe 2 elderly women with progressive, bilateral flexion deformity of the middle and ring fingers. There was no myokymia, and the deformity resembled Dupuytren's contracture, but electromyography showed nearly continuous high-frequency discharges, typical of electrical ne…