Depression did not explain most functional impairment in patients with moderate-to-severe brain injury.
One goal of neuropsychological testing is to predict real-world functioning. However, emotional factors may affect this relationship. In several studies involving neuropsychological testing on patients with traumatic brain injury, depression had a major effect on cognition (see Journal Watch Psychiatry Apr 20 2005 and Apr 5 2006). The current study involved 216 patients with moderate-to-severe TBI who were participants in a post-TBI acute intervention study.
Six months after injury, they underwent assessments of neuropsychological status, depressive symptoms, and everyday functioning. There were significant correlations between the results of neuropsychological tests and everyday functioning. Overall, the correlation of neuropsychological me…
Reviewing Author
DisclosuresRoyaltiesTextbook of Traumatic Brain Injury, 2nd and 3rd editions
Editorial BoardsUpToDate; Journal of Neuropsychiatry and Clinical Neuroscience
Leadership Positions in Professional SocietiesNorth American Brain Injury Association (Board Member); National Institute on Disability, Independent Living, and Rehabilitation Research (Chair of Data Monitoring Safety Board for study of donepezil on cognition after traumatic brain injury)
DisclosuresRoyaltiesTextbook of Traumatic Brain Injury, 2nd and 3rd editions
Editorial BoardsUpToDate; Journal of Neuropsychiatry and Clinical Neuroscience
Leadership Positions in Professional SocietiesNorth American Brain Injury Association (Board Member); National Institute on Disability, Independent Living, and Rehabilitation Research (Chair of Data Monitoring Safety Board for study of donepezil on cognition after traumatic brain injury)