HIV Infection, CRP Levels, and MI Risk

HIV infection and elevated CRP levels each double the risk for heart attack, according to registry data from a large U.S. healthcare system.

Studies suggest that HIV-infected individuals are at increased risk for cardiovascular disease (CVD), but the underlying reasons for that risk are still under investigation. To evaluate how HIV infection and elevated C-reactive protein (CRP) levels each influence risk for acute myocardial infarction (MI), investigators reviewed data from a large patient registry in Massachusetts.

As previously described (JW AIDS Clin Care Dec 8 2008), the analysis included 487 HIV-infected patients and 69,870 HIV-uninfected patients, all of whom had CRP data available from between 1997 and 2006. Patients who had an MI were eligible for analysis only if their most recent CRP level was obtained 3 years to 1 week before the MI.

In a univariate analysis, HIV infe…

Reviewing Author

Keith Henry, MD

Disclosures

Consultant/Advisory BoardViiV Advisory Board

Editorial BoardsJAIDS: Journal of Acquired Immune Deficiency Syndromes

Keith Henry, MD

Disclosures

Consultant/Advisory BoardViiV Advisory Board

Editorial BoardsJAIDS: Journal of Acquired Immune Deficiency Syndromes

HIV Infection, CRP Levels, and MI Risk

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Reviewing Author