Should We Worry about Abnormal Thyroid Function after Iodinated Contrast?

Clinical Takeaway

: In this prospective study, thyroid dysfunction after iodinated contrast occurred in some patients, but all cases were mild, asymptomatic, and resolved without treatment.

Context

High doses of iodine, such as those found in contrast agents for computed tomography (CT) or vascular procedures, can affect thyroid function and lead to either hypothyroidism or hyperthyroidism. However, the clinical relevance of iodinated contrast on thyroid function remains unclear. In this prospective Chinese study, researchers identified 200 patients without known thyroid disease who were scheduled for contrast-enhanced CT or vascular procedures. The patients underwent baseline thyroid ultrasound and thyroid function testing before receiving iodinated contrast media. Follow-up thyroid function testing was performed at 1 week and 1 month after administration of contrast. If abnormalities persisted, additional testing was performe…

Reviewing Author

Ole-Petter Hamnvik, M.B. B.Ch. B.A.O., M.M.Sc., M.R.C.P.I.

Disclosures

Consultant/Advisory BoardMerck

Editorial BoardsEndocrine Practice

Leadership Positions in Professional SocietiesWorld Professional Organization for Transgender Health (Co-lead, Curriculum Development Committee)